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Brain Morphometry BIRN

BIRN’s Morphometry Test Bed focuses on pooling and analyzing data across neuroimaging sites for potential relationships between anatomical differences and specific memory dysfunctions, such as depression, mild Alzheimer’s disease, and mild cognitive impairment.

By acquiring and pooling patient data across sites, scientists are analyzing data from a large group of subjects, in order to investigate what structural brain differences correlate to symptoms of memory dysfunction or depression. This line of research has already uncovered new diagnostic differences and is expected to lead to potential therapies.

Key Personnel

Principal Investigator: Bruce Rosen
Scientific Coordinator: Randy Gollub
Project Manager: Karl Helmer

Organization: 10 Institutions

Brain Imaging and Analysis Center, Duke University
Site Principal Investigator: Ranga Krishnan; Co-PI: James MacFall
fMRI Research Center, University of California, San Diego
Site Principal Investigator: Anders Dale
Brain Imaging Center, University of California, Irvine
Site Principal Investigator: Steven Potkin
Harvard University
Center for Brain Science: Randy Buckner
Center for Functional Neuroimaging Technologies
Massachusetts General Hospital (Submitting Institution)
Site Principal Investigator: David Kennedy; Co-PI: Randy Gollub
Laboratory of Neuro Imaging, University of California, Los Angeles
Site Principal Investigator: Arthur Toga
Center for Image Science, Johns Hopkins University
Site Principal Investigator: Michael Miller; Co-PI: Peter van Zijl
Surgical Planning Lab, Brigham and Women's Hospital
Site Principal Investigator Ron Kikinis
Computer Science & Artificial Intelligence Laboratory
Massachusetts Institute of Technology
Site Principal Investigator: Eric Grimson
Washington University, St Louis
Neuroinformatics Research Group: Dan Marcus

Morphometry BIRN Tools Primer

Morphometry BIRN Brochure 2006, 2007

Morphometry BIRN Publications