Mouse BIRN
The Mouse BIRN Test Bed is helping scientists study neurodegenerative diseases by marshaling multi-modal data from the mouse, as an animal model, to investigate neurological disorders. Researchers across six groups are pooling and analyzing multi-scale structural and functional data and integrating it with genomic and gene expression data acquired from the mouse brain. These correlated multi-scale analyses of data are providing a comprehensive basis upon which to interpret signals from the whole brain relative to the tissue and cellular alterations characteristic of the modeled disorder.
BIRN’s infrastructure is providing the collaborative tools to enable researchers with unique expertise and knowledge of the mouse an opportunity to work together on research relevant to pre-clinical mouse models of neurological disease.
The Mouse BIRN also maintains a collaborative Web wiki, which contains announcements, an FAQ, and much more. Feel free to explore the Mouse BIRN Wiki. You may also wish to consult the Mouse BIRN Sample Queries and the Mouse BIRN Tools Primer.
Key Personnel
Principal Investigator: Art Toga
Scientific Coordinator: Maryann Martone
Project Manager: Seth Ruffins
Organization: 6 Institutions
| Center for In Vivo Microscopy, Duke University Principal Investigator G. Allan Johnson |
MRI Center at the Beckman Institute, California Institute of Technology Principal Investigator Russell Jacobs |
| Drexel University, Lab. Bioimaging & Anatomical Informatics Principal Investigator Jonathan Nissanov |
National Center for Microscopy and Imaging Research, UCSD Principal Investigator Mark Ellisman; Co-PI: Maryann Martone |
| Laboratory of Neuro Imaging, UCLA (Submitting Institution) Principal Investigator Arthur Toga |
University of Tennessee, Memphis - Health Sciences Center Principal Investigator Robert Williams |